Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194863 | 0.83 | SLC6A2 (0.65) | SLC6A2SLC6A4MAPT | |
| SCHEMBL9195174 | 0.77 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL20037238 | 0.72 | SLC6A2 (0.57) | SLC6A2SLC6A4BRD4 | |
| Hydrochloric Acid SCHEMBL3977698 | 0.71 | SLC6A2 (0.49) | SLC6A2SLC6A4MAPT | |
| SCHEMBL20940094 | 0.70 | AAK1 (0.36) | — | |
| SCHEMBL9201002 | 0.69 | SLC6A2 (0.43) | SLC6A2 | |
| SCHEMBL16791935 | 0.69 | CYP11B1 (0.37) | TP53 | |
| SCHEMBL29412428 | 0.68 | SLC6A2 (0.59) | SLC6A2SLC6A4 | |
| SCHEMBL704340 | 0.68 | SLC6A2 (0.59) | SLC6A2SLC6A4 | |
| SCHEMBL9197969 | 0.67 | SLC6A2 (0.65) | SLC6A2SLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | claimed |
| EP-0471296-B1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0471296-A1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |