Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201233 | 0.84 | SLC6A2 (0.70) | SLC6A2SLC6A4HTR2CITGB3ITGAV | |
| SCHEMBL9194455 | 0.83 | SLC6A2 (0.63) | SLC6A2SLC6A4ITGB3ITGAVROCK1 | |
| SCHEMBL8845539 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4ITGB3ITGAV | |
| SCHEMBL9155328 | 0.82 | SLC6A2 (0.56) | SLC6A2ITGB3ITGAV | |
| SCHEMBL8845768 | 0.82 | SLC6A2 (0.68) | SLC6A2SLC6A4ITGB3ITGAVCYP17A1 | |
| SCHEMBL9196729 | 0.79 | SLC6A2 (0.52) | SLC6A2ITGB3ITGAVMAPT | |
| Oxalic Acid SCHEMBL9196754 | 0.79 | SLC6A2 (0.57) | SLC6A2ITGB3ITGAVROCK1 | |
| SCHEMBL9195174 | 0.79 | SLC6A2 (1.00) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL8845716 | 0.78 | SLC6A2 (0.55) | SLC6A2ITGB3ITGAV | |
| SCHEMBL8845725 | 0.77 | SLC6A2 (0.54) | SLC6A2ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | claimed |
| EP-0471296-B1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0471296-A1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |