Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.52 |
| ▸ | MMP12 | P39900 | 3/20 | 0.52 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 3/20 | 0.48 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP10 | P09238 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199101 | 1.00 | USP30 (0.57) | USP30ADAM17MMP12DGAT2YAP1 | |
| SCHEMBL9196648 | 1.00 | USP30 (0.57) | USP30ADAM17MMP12DGAT2YAP1 | |
| SCHEMBL9203806 | 0.88 | CTSK (0.48) | TAOK1TAOK3SLC6A5HDAC3HDAC1 | |
| SCHEMBL7611773 | 0.87 | USP30 (0.62) | USP30ADAM17MMP12DGAT2MMP3 | |
| SCHEMBL2190446 | 0.86 | USP30 (0.67) | USP30ADAM17MMP12DGAT2MMP3 | |
| SCHEMBL9273081 | 0.86 | YAP1 (0.49) | YAP1 | |
| SCHEMBL9199336 | 0.85 | MRGPRX4 (0.49) | TAOK1TAOK3SLC6A5HDAC3HDAC1 | |
| SCHEMBL9199330 | 0.85 | MRGPRX4 (0.49) | TAOK1TAOK3SLC6A5HDAC3HDAC1 | |
| SCHEMBL8194053 | 0.83 | PRMT5 (0.49) | USP30ADAM17MMP12YAP1TAOK1 | |
| SCHEMBL2534996 | 0.81 | CTSK (0.56) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |