Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199330 | 1.00 | MRGPRX4 (0.49) | MRGPRX4SLC6A5HDAC3HDAC1HDAC2 | |
| SCHEMBL9203806 | 0.86 | CTSK (0.48) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9199093 | 0.85 | USP30 (0.57) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9199101 | 0.85 | USP30 (0.57) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9196648 | 0.85 | USP30 (0.57) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9203223 | 0.81 | ADAM17 (0.52) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9391550 | 0.81 | ADAM17 (0.52) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9195973 | 0.78 | ADAM17 (0.51) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9393104 | 0.78 | ADAM17 (0.51) | SLC6A5HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9201097 | 0.77 | FAAH (0.53) | HDAC3HDAC1HDAC2NCOR2TAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |