Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264209 | 0.84 | TDP1 (0.39) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL26002442 | 0.79 | TDP1 (0.41) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL23621461 | 0.79 | TDP1 (0.41) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL9291948 | 0.78 | TSHR (0.33) | TDP1ALDH1A1TSHR | |
| SCHEMBL5148860 | 0.77 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL28680049 | 0.75 | POLB (0.34) | TDP1ALDH1A1TSHR | |
| SCHEMBL6252842 | 0.73 | ALDH1A1 (0.36) | TDP1ALDH1A1TSHRCA2 | |
| SCHEMBL1315674 | 0.72 | ACHE (0.39) | TDP1ALDH1A1TSHRCA2 | |
| SCHEMBL1317490 | 0.72 | ACHE (0.39) | TDP1ALDH1A1TSHRCA2 | |
| SCHEMBL29993728 | 0.72 | CA2 (0.31) | TDP1ALDH1A1TSHRCA2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640091-A4 | SYNTHESIS OF NUCLEOTIDE MONOMERS. | RIBOZYME PHARM INC (US) | 1995-07-26 | — | — | EP | claimed |
| EP-0640091-A1 | SYNTHESIS OF NUCLEOTIDE MONOMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-03-01 | — | — | EP | claimed |
| WO-1993023413-A1 | SYNTHESIS OF NUCLEOTIDE MONOMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1993-11-25 | — | — | WO | claimed |