Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.42 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.42 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9134280 | 0.99 | ACHE (0.47) | ACHEDRD2DRD3BRD4CYP4Z1 | |
| SCHEMBL9195127 | 0.93 | ACHE (0.49) | ACHEDRD2DRD3CYP4F2CYP4A11 | |
| SCHEMBL5679141 | 0.93 | ACHE (0.49) | ACHEDRD2DRD3CYP4F2CYP4A11 | |
| SCHEMBL9191715 | 0.93 | ACHE (0.49) | ACHEDRD2DRD3CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL9133231 | 0.92 | ACHE (0.48) | ACHEDRD2DRD3CYP4Z1CYP4F2 | |
| Hydrochloric Acid SCHEMBL9133151 | 0.92 | ACHE (0.48) | ACHEDRD2DRD3CYP4Z1CYP4F2 | |
| Hydrochloric Acid SCHEMBL9133223 | 0.92 | ACHE (0.48) | ACHEDRD2DRD3CYP4Z1CYP4F2 | |
| SCHEMBL9305655 | 0.84 | BRD4 (0.60) | ACHEDRD2DRD3BRD4 | |
| SCHEMBL9305716 | 0.83 | BRD4 (0.56) | ACHEDRD2DRD3BRD4 | |
| Hydrochloric Acid SCHEMBL9304134 | 0.83 | BRD4 (0.58) | ACHEDRD2DRD3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500443-B1 | Phenylethanolamino- and phenylethanolaminomethyltetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | SANOFI SA (FR) | 1995-04-26 | — | — | EP | disclosed |
| EP-0500443-A1 | Phenylethanolamino- and phenylethanolaminomethyltetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | SANOFI (FR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0499755-A1 | Phenylethanolaminotetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | MIDY S.p.A. (IT) | 1992-08-26 | — | — | EP | disclosed |