SCHEMBL919920

SCHEMBL919920

Cc1ccc(C(=O)NCc2cccc(Oc3ccccc3C)c2)c(N)n1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
USP2 O75604 1/20 0.50
PPARG P37231 8/20 0.49
PPARD Q03181 8/20 0.49
PPARA Q07869 8/20 0.49
MAPK14 Q16539 1/20 0.47
CHRM4 P08173 1/20 0.46
HSD17B10 Q99714 1/20 0.45
GCK P35557 1/20 0.45
MMP13 P45452 1/20 0.44
RAB9A P51151 1/20 0.43
ROCK2 O75116 1/20 0.43
ROCK1 Q13464 1/20 0.43
FFAR1 O14842 1/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920658 0.91 HPGD (0.54) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL919954 0.90 ALDH1A1 (0.48) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL921270 0.90 KDM4E (0.48) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL920702 0.90 KDM4E (0.48) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL920667 0.90 HPGD (0.48) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL921769 0.90 KDM4E (0.48) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL920750 0.89 KDM4E (0.54) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL921442 0.89 MAPK14 (0.58) KDM4EALDH1A1HPGDMAPK14
SCHEMBL920016 0.88 PPARG (0.49) KDM4EALDH1A1HPGDUSP2PPARG
SCHEMBL921775 0.88 KDM4E (0.48) KDM4EALDH1A1HPGDUSP2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KDM4E 3657/4885ALDH1A1 2743/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.