SCHEMBL919950

SCHEMBL919950

CSc1ccc(Oc2cc[c]cc2)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 10/20 0.44
HSP90AA1 P07900 1/20 0.35
AR P10275 2/20 0.34
SOS1 Q07889 1/20 0.33
HTR2A P28223 8/20 0.32
KCNH2 Q12809 7/20 0.32
KMO O15229 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
FFAR1 O14842 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920360 0.83 CNR2 (0.34) SLC6A4HSP90AA1ARSOS1HTR2A
SCHEMBL922829 0.81 HTR2A (0.43) SLC6A4ARHTR2AKCNH2CYP3A4
SCHEMBL920631 0.79 AR (0.42) SLC6A4ARALDH1A1CYP3A4TSHR
SCHEMBL693602 0.78 HSP90AA1 (0.55) SLC6A4HSP90AA1HTR2AKCNH2KMO
SCHEMBL920787 0.78 ST14 (0.53) SLC6A4
SCHEMBL919559 0.78 SLC6A4 (0.34) SLC6A4HTR2AKCNH2ALDH1A1CYP3A4
SCHEMBL3235096 0.77 HTR2A (0.47) SLC6A4HSP90AA1ARSOS1HTR2A
SCHEMBL3240008 0.75 SLC6A4 (0.42) SLC6A4ARHTR2AKCNH2ALDH1A1
SCHEMBL10924833 0.74 SLC6A4 (0.43) SLC6A4HSP90AA1HTR2AKCNH2ALDH1A1
SCHEMBL921574 0.74 SOS1 (0.57) SLC6A4HSP90AA1ARSOS1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 SLC6A4 2590/4885HSP90AA1 1854/4885AR 4285/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 SLC6A4 3323/4885HSP90AA1 1811/4885AR 1048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.