SCHEMBL921574

SCHEMBL921574

Fc1ccc(Oc2cc[c]cc2)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 4/20 0.57
HTR2A P28223 5/20 0.47
SLC6A4 P31645 5/20 0.47
KCNH2 Q12809 5/20 0.47
EGFR P00533 1/20 0.43
KDR P35968 2/20 0.40
CHEK2 O96017 1/20 0.40
HSP90AA1 P07900 1/20 0.38
AR P10275 1/20 0.37
NPC1 O15118 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4345160 0.86 SOS1 (0.65) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL2752328 0.82 SOS1 (0.53) SOS1HTR2ASLC6A4KCNH2AR
SCHEMBL693602 0.82 HSP90AA1 (0.55) HTR2ASLC6A4KCNH2HSP90AA1
SCHEMBL14662201 0.81 SOS1 (0.60) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL27903184 0.80 SOS1 (0.48) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL10875782 0.79 SOS1 (0.58) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL26601050 0.79 SOS1 (0.58) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL10876069 0.79 SOS1 (0.58) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL1979103 0.79 SOS1 (0.63) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL3235096 0.78 HTR2A (0.47) SOS1HTR2ASLC6A4KCNH2CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 SOS1 768/4885HTR2A 4680/4885SLC6A4 2590/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 SOS1 385/4885HTR2A 3803/4885SLC6A4 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.