Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204759 | 0.93 | SLC6A3 (0.40) | SLC6A3PRKDCPOLBPIK3CDPIK3CB | |
| SCHEMBL9198960 | 0.92 | TDP1 (0.37) | SLC6A3PRKDCPOLBPIK3CDPIK3CB | |
| SCHEMBL9200491 | 0.86 | APAF1 (0.39) | SLC6A3PRKDCPOLBPIK3CDPIK3CB | |
| SCHEMBL9203404 | 0.86 | PARP1 (0.41) | PRKDCPOLBNPC1ALDH1A1TSHR | |
| SCHEMBL9196278 | 0.85 | APAF1 (0.39) | PRKDCPOLBNPC1MEN1KMT2A | |
| SCHEMBL9202762 | 0.85 | AKR1C3 (0.35) | SLC6A3PRKDCPIK3CDPIK3CBMEN1 | |
| SCHEMBL9203236 | 0.83 | PARP1 (0.44) | SLC6A3PRKDCPOLBKDM4EALDH1A1 | |
| SCHEMBL9201620 | 0.82 | NPC1 (0.37) | SLC6A3PRKDCPOLBPIK3CDPIK3CB | |
| SCHEMBL9200324 | 0.81 | NPC1 (0.38) | POLBNPC1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL9195793 | 0.81 | BCHE (0.39) | POLBNPC1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575425-B1 | USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-11 | — | — | EP | disclosed |