Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197878 | 0.86 | ABCC9 (0.37) | ABCC9KCNE1KCNQ1CYP1A2CYP2D6 | |
| SCHEMBL9197771 | 0.86 | ABCC9 (0.36) | ABCC9DDB1CRBNKCNE1KCNQ1 | |
| SCHEMBL9197583 | 0.84 | ABCC9 (0.35) | ABCC9DDB1CRBNKCNE1KCNQ1 | |
| SCHEMBL9192327 | 0.83 | ABCC9 (0.54) | ABCC9KCNE1KCNQ1ABCC8KCNJ11 | |
| SCHEMBL9198494 | 0.83 | ABCC9 (0.44) | ABCC9DDB1CRBNLMNAL3MBTL1 | |
| SCHEMBL9200125 | 0.82 | ABCC9 (0.36) | ABCC9DDB1CRBNL3MBTL1 | |
| SCHEMBL9199615 | 0.82 | ABCB1 (0.39) | ABCC9KCNE1KCNQ1LMNA | |
| SCHEMBL9195764 | 0.81 | RAB9A (0.37) | CYP1A2CYP2C19 | |
| SCHEMBL9194966 | 0.81 | ABCC9 (0.35) | ABCC9DDB1CRBNKCNE1KCNQ1 | |
| SCHEMBL9197134 | 0.81 | ABCC9 (0.38) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406656-B1 | Chroman derivatives | MERCK PATENT GMBH (DE) | 1995-01-11 | — | — | EP | disclosed |
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0406656-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |