Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203707 | 0.84 | DHODH (0.56) | KCNK3KCNK9KMT2ARAB9AALDH1A1 | |
| SCHEMBL9202946 | 0.83 | KMT2A (0.51) | KMT2AMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL9204465 | 0.83 | F2R (0.52) | KMT2AMAPTRAB9AALDH1A1POLB | |
| SCHEMBL9199984 | 0.83 | TDP1 (0.54) | KCNK3KCNK9KMT2AMAPTALDH1A1 | |
| SCHEMBL9198091 | 0.83 | HTT (0.66) | KCNK3KCNK9KMT2AMAPTRAB9A | |
| SCHEMBL9205708 | 0.82 | KCNK3 (0.56) | KCNK3KCNK9KMT2AMAPTMAPK1 | |
| SCHEMBL11594247 | 0.77 | KCNK3 (0.71) | KCNK3KCNK9KMT2AMAPTMAPK1 | |
| SCHEMBL3050016 | 0.77 | KCNK3 (0.70) | KCNK3KCNK9KMT2AMAPTMAPK1 | |
| SCHEMBL9200578 | 0.76 | HPGD (0.49) | KMT2AMAPTMAPK1RAB9ANPC1 | |
| SCHEMBL11795078 | 0.76 | KCNK3 (0.73) | KCNK3KCNK9KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |