Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203707 | 0.86 | DHODH (0.56) | F2RGAAKMT2AMEN1NPC1 | |
| SCHEMBL9199984 | 0.85 | TDP1 (0.54) | GAAMAPTKMT2AMEN1LMNA | |
| SCHEMBL9202946 | 0.85 | KMT2A (0.51) | F2RGAAMAPTKMT2AMEN1 | |
| SCHEMBL9198091 | 0.85 | HTT (0.66) | GAAMAPTKMT2AMEN1NPC1 | |
| SCHEMBL9199688 | 0.83 | KCNK3 (0.65) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9201424 | 0.78 | LMNA (0.49) | GAAMAPTKMT2AMEN1NPC1 | |
| SCHEMBL9205680 | 0.77 | SMN1; SMN2 (0.53) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27408754 | 0.77 | KMT2A (0.60) | F2RGAAMAPTKMT2AMEN1 | |
| SCHEMBL9204272 | 0.76 | AKR1C3 (0.57) | GAAMAPTKMT2AMEN1NPC1 | |
| SCHEMBL9200578 | 0.76 | HPGD (0.49) | GAAMAPTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |