Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 5/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199111 | 0.83 | FADS1 (0.59) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL9199688 | 0.82 | KCNK3 (0.65) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL11594247 | 0.78 | KCNK3 (0.71) | KCNK3KCNK9MAPTRAB9AMAPK1 | |
| SCHEMBL3050016 | 0.78 | KCNK3 (0.70) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL11795078 | 0.77 | KCNK3 (0.73) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL2362772 | 0.76 | KMT2A (0.82) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL4428019 | 0.74 | MAPT (0.71) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL6294966 | 0.74 | PNLIP (0.70) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL11789635 | 0.74 | KCNK3 (0.68) | KCNK3KCNK9KDM4EMAPTRAB9A | |
| SCHEMBL24118801 | 0.73 | GRM5 (0.83) | KCNK3KCNK9KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |