Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527107 | 0.83 | TSHR (0.48) | HTTPOLBHPGDTSHRNPSR1 | |
| SCHEMBL9377323 | 0.80 | HTT (0.43) | HTTCNR2POLBHPGDTSHR | |
| SCHEMBL9200545 | 0.78 | PTGS1 (0.35) | HTTPOLBPTGS1NPSR1ALDH1A1 | |
| SCHEMBL9201823 | 0.78 | ALDH1A1 (0.37) | HTTPOLBTSHRKMT2AMEN1 | |
| SCHEMBL14676577 | 0.76 | HPGD (0.56) | HTTCNR2POLBHPGDTSHR | |
| SCHEMBL9199739 | 0.75 | HTT (0.50) | HTTCNR2POLBPTGS1HPGD | |
| SCHEMBL8307876 | 0.71 | HTT (0.38) | HTTCNR2POLBHPGDTSHR | |
| SCHEMBL13438 | 0.70 | PTGS1 (0.69) | HTTPTGS1NPSR1KMT2AMEN1 | |
| SCHEMBL371239 | 0.69 | HTT (0.48) | HTTCNR2POLBHPGDTSHR | |
| SCHEMBL10446051 | 0.69 | HTT (0.48) | HTTCNR2POLBPTGS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418667-B1 | Carboxylic acid amides | BASF AG (DE) | 1995-08-16 | — | — | EP | disclosed |
| EP-0418667-A2 | Carboxylic acid amides | BASF Aktiengesellschaft (DE) | 1991-03-27 | — | — | EP | disclosed |