Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.69 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | RAF1 | P04049 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205457 | 0.84 | AR (0.75) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL6094870 | 0.84 | CYP3A4 (0.85) | ARCYP3A4MAPTMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL30630415 | 0.82 | AR (1.00) | ARCYP3A4MAPTMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL2390993 | 0.82 | AR (1.00) | ARCYP3A4MAPTMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL158303 | 0.82 | AR (1.00) | ARCYP3A4MAPTMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL28317755 | 0.81 | AR (0.97) | ARCYP3A4MAPTMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL2390943 | 0.81 | AR (0.97) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL311760 | 0.81 | AR (0.68) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4649971 | 0.80 | CYP3A4 (1.00) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1647031 | 0.78 | TNKS (0.69) | ARCYP3A4MAPTKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430693-B1 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS (JP) | 1995-05-31 | — | — | EP | disclosed |
| US-5114941-A | PYRIMIDINEDIONE DERIVATIVE COMPOUNDS, METHOD FOR PREPARING SAME, AND ANTIARRYTHMIC AGENTS CONTAINING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0430693-A2 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-06-05 | — | — | EP | disclosed |