Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199813 | 0.86 | MLNR (0.41) | GAAL3MBTL1XIAPPRKCAMLNR | |
| SCHEMBL9195760 | 0.83 | ALDH1A1 (0.33) | GAAL3MBTL1ALDH1A1PRKCAWRN | |
| SCHEMBL9199610 | 0.82 | XIAP (0.40) | XIAPPRKCAHTR2AADRA1AHTR2B | |
| SCHEMBL7444813 | 0.82 | KMT2A (0.38) | HPGDKMT2AALDH1A1MLNRNR1I2 | |
| SCHEMBL6177878 | 0.81 | MLNR (0.38) | GAAL3MBTL1PRKCAWRNMLNR | |
| SCHEMBL6173128 | 0.81 | OPRD1 (0.41) | GAAL3MBTL1PRKCAWRNMLNR | |
| SCHEMBL9196032 | 0.80 | PRKCA (0.39) | GAAL3MBTL1XIAPPRKCA | |
| SCHEMBL6176450 | 0.79 | MLNR (0.49) | GAAL3MBTL1ALDH1A1PRKCAWRN | |
| SCHEMBL7443043 | 0.79 | MLNR (0.42) | GAAL3MBTL1KMT2APRKCAWRN | |
| SCHEMBL9195762 | 0.78 | PRKCA (0.35) | GAAL3MBTL1PRKCAWRNMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |