Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183256 | 0.73 | SCN9A (0.37) | SCN9AKCNK13 | |
| SCHEMBL4909130 | 0.72 | — | — | |
| SCHEMBL155358 | 0.71 | KDM4E (0.52) | — | |
| SCHEMBL2340955 | 0.70 | — | — | |
| SCHEMBL3759300 | 0.68 | MDM2 (0.31) | — | |
| SCHEMBL359859 | 0.68 | METAP2 (0.37) | — | |
| SCHEMBL8096032 | 0.68 | PPARA (0.37) | — | |
| SCHEMBL1198354 | 0.67 | CYP2A6 (0.37) | — | |
| SCHEMBL22388750 | 0.67 | SCN9A (0.37) | SCN9AKCNK13F2RL1 | |
| SCHEMBL1925074 | 0.67 | GOT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683772-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1995-11-29 | — | — | EP | disclosed |
| EP-0683772-A4 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1995-09-27 | — | — | EP | disclosed |