Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 4/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860936 | 0.92 | MCL1 (0.54) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL30395677 | 0.89 | PPARD (0.56) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL4478676 | 0.89 | PPARD (0.56) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL6384598 | 0.89 | SRD5A2 (0.55) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL6385516 | 0.86 | ITGB3 (0.60) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL27619992 | 0.85 | MCL1 (0.55) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL9209065 | 0.83 | CYSLTR1 (0.63) | PPARDPPARAPPARG | |
| SCHEMBL6099158 | 0.82 | BCL2 (0.55) | SRD5A2BCL2MCL1MEN1KMT2A | |
| SCHEMBL27587634 | 0.82 | BCL2 (0.56) | SRD5A2BCL2MCL1PPARDPPARA | |
| SCHEMBL2156900 | 0.82 | PLA2G2A (0.56) | BCL2MCL1NPC1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544821-B1 | INDOLE DERIVATIVES AS ANTIALLERGY AND ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5290788-A | Indole derivatives as antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1994-03-01 | — | — | US | disclosed |