Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203501 | 0.82 | GABBR2 (0.39) | AKR1C3AKR1C2MEN1KMT2ACYP1A2 | |
| SCHEMBL9196668 | 0.82 | MAPT (0.44) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL9198986 | 0.80 | GABBR2 (0.43) | KDM4EMEN1KMT2ACYP1A2TSHR | |
| SCHEMBL9196657 | 0.79 | GABBR2 (0.41) | MEN1KMT2ACYP1A2TSHRCYP2C9 | |
| SCHEMBL9315751 | 0.79 | GABBR2 (0.41) | MEN1KMT2ACYP1A2TSHRCYP2C9 | |
| SCHEMBL9202387 | 0.79 | GABBR2 (0.51) | MEN1KMT2ACYP1A2TSHRCYP2C9 | |
| SCHEMBL9315726 | 0.79 | AKR1C3 (0.41) | AKR1C3AKR1C2ALDH2MAOAMAOB | |
| SCHEMBL9195308 | 0.79 | GAA (0.41) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9200327 | 0.76 | ALDH1A1 (0.45) | AKR1C3AKR1C2MAOBKDM4EALDH1A1 | |
| SCHEMBL9594090 | 0.76 | PIM1 (0.39) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463969-B1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR (FR) | 1995-02-08 | — | — | EP | claimed |
| US-5162364-A | Treatment of spastic and senescence disorders | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |