Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203506 | 0.81 | LMNA (0.43) | MEN1BLMKMT2AAKR1C3AKR1C2 | |
| SCHEMBL9196674 | 0.81 | MAOB (0.47) | MEN1BLMKMT2ATAS1R3TAS1R1 | |
| SCHEMBL9315754 | 0.79 | PIM1 (0.55) | ALDH1A1MAPK1CA12CA1CA9 | |
| SCHEMBL9198993 | 0.79 | GABBR2 (0.44) | MEN1BLMKMT2AKDM4ECYP1A2 | |
| SCHEMBL9202393 | 0.78 | GABBR2 (0.54) | ALDH1A1HSD17B10MEN1BLMKMT2A | |
| SCHEMBL9196666 | 0.78 | GABBR2 (0.43) | MEN1BLMKMT2ACA12CA1 | |
| SCHEMBL9315720 | 0.78 | AKR1C3 (0.46) | ALDH1A1HPGDHSD17B10MEN1POLB | |
| SCHEMBL9195312 | 0.78 | GAA (0.43) | ALDH1A1MEN1BLMKMT2ACYP1A2 | |
| SCHEMBL9200322 | 0.76 | AKR1C3 (0.41) | ALDH1A1HPGDHSD17B10MEN1POLB | |
| SCHEMBL5866928 | 0.76 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463969-B1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR (FR) | 1995-02-08 | — | — | EP | claimed |
| US-5162364-A | Treatment of spastic and senescence disorders | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |