Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198805 | 0.89 | EPHX2 (0.38) | EPHX2NR1H4HDAC8ACHEMAOB | |
| SCHEMBL9286479 | 0.87 | ACHE (0.39) | EPHX2NR1H4HDAC8ACHEMAOB | |
| SCHEMBL9198798 | 0.87 | HDAC8 (0.40) | EPHX2NR1H4HDAC8ACHEMAOB | |
| SCHEMBL9202752 | 0.85 | HDAC8 (0.39) | EPHX2NR1H4HDAC8ACHEMAOB | |
| SCHEMBL9206718 | 0.84 | HSD17B2 (0.40) | MAOBALDH1A1HPGDSMN1; SMN2TUBB1 | |
| SCHEMBL9206463 | 0.83 | CACNA1B (0.39) | EPHX2NR1H4HDAC8ACHEALDH1A1 | |
| SCHEMBL9207327 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2CA1CA2 | |
| SCHEMBL9111696 | 0.81 | EPHX2 (0.46) | EPHX2NR1H4MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL9200672 | 0.79 | CYP4F2 (0.39) | ACHEALDH1A1HPGDSMN1; SMN2TUBB1 | |
| SCHEMBL9204247 | 0.78 | CYP3A4 (0.37) | ALDH1A1HPGDSMN1; SMN2TUBB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |