Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 7/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979808 | 0.91 | BRS3 (0.48) | BRS3AGTR2AGTR1 | |
| SCHEMBL9276385 | 0.91 | BRS3 (0.41) | BRS3FOLH1DHODHAGTR2AGTR1 | |
| SCHEMBL9200610 | 0.86 | BRS3 (0.42) | BRS3AGTR2AGTR1 | |
| SCHEMBL9202373 | 0.83 | ACHE (0.39) | BRS3AGTR2AGTR1 | |
| SCHEMBL9270036 | 0.82 | AGTR1 (0.38) | BRS3AGTR2AGTR1 | |
| SCHEMBL8979847 | 0.81 | BRS3 (0.47) | BRS3AGTR2AGTR1 | |
| SCHEMBL8979807 | 0.81 | BRS3 (0.47) | BRS3AGTR2AGTR1 | |
| SCHEMBL9200181 | 0.80 | AGTR1 (0.40) | BRS3AGTR2AGTR1 | |
| SCHEMBL8979815 | 0.78 | BRS3 (0.48) | BRS3AGTR2AGTR1 | |
| SCHEMBL9203240 | 0.78 | PPARG (0.36) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |