Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979817 | 0.91 | AGTR2 (0.51) | BRS3AGTR2AGTR1 | |
| SCHEMBL9276388 | 0.91 | BRS3 (0.41) | BRS3AGTR2AGTR1ALDH1A1 | |
| SCHEMBL9200596 | 0.86 | BRS3 (0.42) | BRS3AGTR2AGTR1 | |
| SCHEMBL8979907 | 0.84 | AGTR1 (0.46) | BRS3AGTR2AGTR1 | |
| SCHEMBL9202381 | 0.83 | ACHE (0.39) | AGTR2AGTR1ALDH1A1 | |
| SCHEMBL9270044 | 0.82 | AGTR1 (0.38) | BRS3AGTR2AGTR1ALDH1A1 | |
| SCHEMBL8979812 | 0.81 | AGTR2 (0.50) | BRS3AGTR2AGTR1 | |
| SCHEMBL8979855 | 0.81 | AGTR1 (0.50) | BRS3AGTR2AGTR1 | |
| SCHEMBL9198030 | 0.80 | AGTR1 (0.40) | BRS3AGTR2AGTR1 | |
| SCHEMBL9200830 | 0.78 | RNASEH1 (0.46) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |