Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 3/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811922 | 0.81 | ALOX15 (0.41) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL8304285 | 0.80 | CUL4A (0.38) | ALDH1A1CUL4ATYMSSOAT1KMT2A | |
| SCHEMBL10972566 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CUL4ATYMSSOAT1KMT2A | |
| SCHEMBL22426580 | 0.74 | — | — | |
| SCHEMBL10974715 | 0.71 | ALDH1A1 (0.43) | ALDH1A1CUL4ATYMSSOAT1KMT2A | |
| SCHEMBL5410864 | 0.71 | TSHR (0.50) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL10352276 | 0.71 | KMT2A (0.44) | ALDH1A1CUL4ATYMSSOAT1KMT2A | |
| SCHEMBL8516383 | 0.70 | TSHR (0.52) | ALDH1A1TYMSSOAT1KMT2AKDM4E | |
| SCHEMBL12315105 | 0.68 | TNF (0.47) | ALDH1A1TYMSKMT2AKDM4EMEN1 | |
| SCHEMBL14363150 | 0.68 | CYP1A2 (0.46) | ALDH1A1CUL4ATYMSSOAT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638074-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF Aktiengesellschaft (DE) | 1995-02-15 | — | — | EP | disclosed |