Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200767 | 0.80 | ALDH1A1 (0.40) | CUL4ATYMSALDH1A1KMT2AKDM4E | |
| SCHEMBL10972566 | 0.70 | ALDH1A1 (0.48) | CUL4ATYMSALDH1A1KMT2AKDM4E | |
| SCHEMBL10974715 | 0.66 | ALDH1A1 (0.43) | CUL4ATYMSALDH1A1KMT2AKDM4E | |
| SCHEMBL10352276 | 0.66 | KMT2A (0.44) | CUL4ATYMSALDH1A1KMT2AKDM4E | |
| SCHEMBL10652359 | 0.65 | ALDH1A1 (0.44) | CUL4ATYMSALDH1A1KDM4ELMNA | |
| SCHEMBL8516383 | 0.64 | TSHR (0.52) | TYMSALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL11215883 | 0.64 | HPGD (0.36) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL9537331 | 0.64 | — | — | |
| SCHEMBL8560927 | 0.64 | ALOX5 (0.41) | CUL4ATYMSALDH1A1KMT2AMEN1 | |
| SCHEMBL3997981 | 0.64 | CUL4A (0.48) | CUL4AALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638074-B1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0638074-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF Aktiengesellschaft (DE) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993022295-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |