Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845104 | 0.83 | CCR1 (0.52) | CCR1LMNAALDH1A1 | |
| SCHEMBL9426817 | 0.79 | CCR1 (0.45) | CCR1LMNAALDH1A1 | |
| SCHEMBL8255534 | 0.79 | CCR1 (0.45) | CCR1LMNAALDH1A1 | |
| SCHEMBL8251316 | 0.79 | CCR1 (0.45) | CCR1LMNAALDH1A1 | |
| SCHEMBL13548795 | 0.78 | CCR1 (0.44) | CCR1LMNAALDH1A1 | |
| SCHEMBL13552352 | 0.76 | CCR1 (0.44) | CCR1LMNAALDH1A1 | |
| SCHEMBL7675246 | 0.75 | LMNA (0.54) | CCR1LMNAALDH1A1KDM4E | |
| SCHEMBL9198384 | 0.75 | CCR1 (0.43) | CCR1LMNAALDH1A1 | |
| SCHEMBL11730664 | 0.73 | CCR1 (0.44) | CCR1 | |
| SCHEMBL13806618 | 0.73 | CCR1 (0.41) | CCR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456183-B1 | Spiro dibenzosuberane derivatives | SHIONOGI & CO (JP) | 1995-10-04 | — | — | EP | disclosed |
| EP-0456183-A2 | Spiro dibenzosuberane derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-11-13 | — | — | EP | disclosed |