Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200773 | 0.83 | CCR1 (0.51) | CCR1LMNAALDH1A1 | |
| SCHEMBL11085131 | 0.81 | CCR1 (0.37) | CCR1 | |
| SCHEMBL9426817 | 0.80 | CCR1 (0.45) | CCR1LMNAHTR2AALDH1A1 | |
| SCHEMBL8251316 | 0.80 | CCR1 (0.45) | CCR1LMNAHTR2AALDH1A1 | |
| SCHEMBL8255534 | 0.80 | CCR1 (0.45) | CCR1LMNAHTR2AALDH1A1CYP2D6 | |
| SCHEMBL13548795 | 0.79 | CCR1 (0.44) | CCR1LMNAHTR2AALDH1A1CYP2D6 | |
| SCHEMBL13552352 | 0.77 | CCR1 (0.44) | CCR1LMNAHTR2AALDH1A1 | |
| SCHEMBL7675246 | 0.76 | LMNA (0.54) | CCR1LMNAHTR2AALDH1A1TP53 | |
| SCHEMBL9198384 | 0.76 | CCR1 (0.43) | CCR1LMNAHTR2AALDH1A1SIGMAR1 | |
| SCHEMBL13867524 | 0.75 | LMNA (0.52) | CCR1LMNAHTR2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456183-A2 | Spiro dibenzosuberane derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-11-13 | — | — | EP | disclosed |