Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201957 | 0.77 | POLB (0.51) | POLBPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5641249 | 0.74 | MAPT (0.58) | POLBMAPTTP53NOTUMTHRB | |
| SCHEMBL7418419 | 0.72 | CCKBR (0.53) | — | |
| SCHEMBL8073114 | 0.72 | TMEM97 (0.49) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL11231189 | 0.72 | NPSR1 (0.61) | POLBMAPTTP53NOTUMTHRB | |
| SCHEMBL7367008 | 0.71 | PREP (0.48) | LMNANPC1RAB9A | |
| SCHEMBL28663653 | 0.71 | SMN1; SMN2 (0.54) | LMNAL3MBTL1 | |
| SCHEMBL7423982 | 0.71 | NOTUM (0.47) | POLBPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29035758 | 0.71 | POLB (0.54) | POLBMAPTTHRB | |
| SCHEMBL7423680 | 0.71 | L3MBTL1 (0.52) | POLBPTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |