Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617072 | 0.82 | NPC1 (0.50) | L3MBTL1NPC1RAB9APOLBNOTUM | |
| SCHEMBL876242 | 0.82 | CASP1 (0.48) | NPC1RAB9APOLBALDH1A1GAA | |
| SCHEMBL7423982 | 0.82 | NOTUM (0.47) | L3MBTL1NPC1RAB9APOLBNOTUM | |
| SCHEMBL7420002 | 0.81 | POLB (0.40) | L3MBTL1NPC1RAB9APOLBNOTUM | |
| SCHEMBL6178448 | 0.81 | NPC1 (0.43) | L3MBTL1NPC1RAB9ANOTUMGAA | |
| SCHEMBL6178825 | 0.81 | GAA (0.45) | L3MBTL1NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL7045087 | 0.79 | NPC1 (0.61) | L3MBTL1NPC1RAB9APOLBNOTUM | |
| SCHEMBL7414937 | 0.79 | L3MBTL1 (0.42) | L3MBTL1NPC1RAB9APOLBNOTUM | |
| SCHEMBL7416761 | 0.78 | POLB (0.41) | L3MBTL1NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL9196586 | 0.78 | L3MBTL1 (0.39) | L3MBTL1NPC1RAB9APOLBPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |