Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199993 | 0.96 | RNASEH1 (0.44) | RNASEH1BRS3 | |
| SCHEMBL8979814 | 0.91 | AGTR1 (0.48) | RNASEH1BRS3 | |
| SCHEMBL9198030 | 0.89 | AGTR1 (0.40) | BRS3 | |
| SCHEMBL9286819 | 0.86 | AGTR1 (0.47) | BRS3 | |
| SCHEMBL9202381 | 0.84 | ACHE (0.39) | — | |
| SCHEMBL9196627 | 0.83 | AGTR1 (0.55) | BRS3 | |
| SCHEMBL9270044 | 0.83 | AGTR1 (0.38) | BRS3 | |
| SCHEMBL9199623 | 0.83 | AGTR1 (0.36) | — | |
| SCHEMBL8979880 | 0.82 | AGTR1 (0.49) | BRS3 | |
| SCHEMBL9200318 | 0.81 | AGTR1 (0.44) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |