Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9211068 | 0.91 | ROCK2 (0.45) | CHIAKDM4EALDH1A1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL9203459 | 0.89 | CHIA (0.43) | CHIADRD4LSSROCK2ROCK1 | |
| SCHEMBL9209529 | 0.89 | CHIA (0.43) | CHIADRD4MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL9202408 | 0.85 | CHIA (0.45) | CHIADRD4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9212196 | 0.85 | CHIA (0.40) | CHIADRD4MCHR1NPC1RAB9A | |
| SCHEMBL9202385 | 0.85 | HTT (0.48) | CHIAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9210225 | 0.83 | CHIA (0.46) | CHIALSSKMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL9205634 | 0.82 | CHIA (0.43) | CHIANPC1RAB9A | |
| SCHEMBL9209130 | 0.81 | CHIA (0.43) | CHIALSSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9208982 | 0.81 | CHIA (0.41) | CHIAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |