Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209529 | 0.88 | CHIA (0.43) | KMT2AMEN1L3MBTL1CHIALMNA | |
| Hydrochloric Acid SCHEMBL9203459 | 0.88 | CHIA (0.43) | L3MBTL1CHIALMNANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9211068 | 0.85 | ROCK2 (0.45) | ALDH1A1KMT2AMEN1CHIA | |
| SCHEMBL9200832 | 0.85 | CYP11B1 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1MCHR1 | |
| Hydrochloric Acid SCHEMBL9202408 | 0.84 | CHIA (0.45) | L3MBTL1CHIANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9212196 | 0.84 | CHIA (0.40) | MCHR1L3MBTL1CHIANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7463749 | 0.83 | HTT (0.54) | HTTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9210225 | 0.83 | CHIA (0.46) | KMT2AMCHR1L3MBTL1CHIALMNA | |
| Hydrochloric Acid SCHEMBL9205634 | 0.81 | CHIA (0.43) | L3MBTL1CHIANPC1RAB9AMGLL | |
| SCHEMBL9209130 | 0.81 | CHIA (0.43) | KMT2AMEN1L3MBTL1CHIALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |