Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210225 | 0.88 | CHIA (0.46) | CHIAL3MBTL3L3MBTL1KMT2AABL1 | |
| Hydrochloric Acid SCHEMBL9203459 | 0.85 | CHIA (0.43) | CHIAL3MBTL3L3MBTL1ABL1RIN1 | |
| SCHEMBL9209529 | 0.85 | CHIA (0.43) | CHIAL3MBTL3L3MBTL1KMT2AABL1 | |
| Hydrochloric Acid SCHEMBL9205634 | 0.83 | CHIA (0.43) | CHIAL3MBTL1ABL1RIN1 | |
| Hydrochloric Acid SCHEMBL9209408 | 0.83 | CHIA (0.44) | CHIAL3MBTL3L3MBTL1KMT2AABL1 | |
| Hydrochloric Acid SCHEMBL9202408 | 0.82 | CHIA (0.45) | CHIAL3MBTL3L3MBTL1ABL1RIN1 | |
| Hydrochloric Acid SCHEMBL9211396 | 0.82 | MCHR1 (0.47) | L3MBTL3LSS | |
| Hydrochloric Acid SCHEMBL9211068 | 0.82 | ROCK2 (0.45) | CHIAKMT2AMEN1 | |
| SCHEMBL7476105 | 0.82 | RAB9A (0.49) | CHIAGRM5VNN1L3MBTL3KMT2A | |
| SCHEMBL9200832 | 0.81 | CYP11B1 (0.41) | CHIAKMT2AMEN1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |