Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544343 | 0.77 | SLC6A2 (0.53) | — | |
| SCHEMBL9198601 | 0.76 | SLC6A2 (0.59) | CYP19A1F10 | |
| SCHEMBL8545162 | 0.75 | SLC6A2 (0.57) | — | |
| SCHEMBL9196106 | 0.75 | MAOB (0.46) | PPARGHTR6HDAC1HDAC2HDAC10 | |
| SCHEMBL6840362 | 0.74 | PLG (0.53) | HTR6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL334423 | 0.72 | ALDH1A1 (0.60) | SLC6A9KDM4C | |
| SCHEMBL9200859 | 0.72 | HTR6 (0.50) | HTR6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL8845761 | 0.70 | HTR6 (0.49) | HTR6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL11959087 | 0.70 | HTR2A (0.51) | HTR6HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9200955 | 0.70 | S1PR1 (0.43) | HTR6HDAC1HDAC2HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471298-B1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-02 | — | — | EP | claimed |