Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGAV | P06756 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192640 | 0.79 | SLC6A2 (0.57) | SLC6A2MAPTITGB3ITGAVLMNA | |
| SCHEMBL9201233 | 0.77 | SLC6A2 (0.70) | SLC6A2SLC6A4ITGB3ITGAVCYP19A1 | |
| SCHEMBL8545162 | 0.77 | SLC6A2 (0.57) | SLC6A2 | |
| SCHEMBL9198615 | 0.77 | SLC6A2 (0.59) | SLC6A2SLC6A4ALDH1A1MAPTITGB3 | |
| SCHEMBL9200852 | 0.76 | PPARG (0.46) | F10CYP19A1 | |
| SCHEMBL8845768 | 0.76 | SLC6A2 (0.68) | SLC6A2SLC6A4ALDH1A1MAPTITGB3 | |
| SCHEMBL9195174 | 0.76 | SLC6A2 (1.00) | SLC6A2SLC6A4CYP17A1 | |
| Oxalic Acid SCHEMBL9196754 | 0.75 | SLC6A2 (0.57) | SLC6A2ITGB3ITGAVITGB5 | |
| SCHEMBL8845725 | 0.75 | SLC6A2 (0.54) | SLC6A2ITGB3ITGAVITGB5 | |
| SCHEMBL8544343 | 0.75 | SLC6A2 (0.53) | SLC6A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471298-B1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-02 | — | — | EP | claimed |