Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205841 | 1.00 | ABCC9 (0.54) | ABCC9KCNA5KCNE1KCNQ1HTR6 | |
| SCHEMBL9200759 | 0.84 | KCNE1 (0.45) | ABCC9KCNA5KCNE1KCNQ1 | |
| SCHEMBL9200746 | 0.84 | KCNE1 (0.45) | ABCC9KCNA5KCNE1KCNQ1 | |
| SCHEMBL9200749 | 0.84 | KCNE1 (0.45) | ABCC9KCNA5KCNE1KCNQ1 | |
| SCHEMBL9869923 | 0.82 | ABCC9 (0.52) | ABCC9KCNA5KCNE1KCNQ1HTR6 | |
| SCHEMBL9203130 | 0.82 | ABCC9 (0.52) | ABCC9KCNA5KCNE1KCNQ1HTR6 | |
| SCHEMBL9869911 | 0.82 | ABCC9 (0.52) | ABCC9KCNA5KCNE1KCNQ1HTR6 | |
| SCHEMBL9200400 | 0.81 | KCNE1 (0.45) | ABCC9KCNA5KCNE1KCNQ1 | |
| SCHEMBL9200392 | 0.81 | KCNE1 (0.45) | ABCC9KCNA5KCNE1KCNQ1 | |
| SCHEMBL9200412 | 0.81 | KCNE1 (0.45) | ABCC9KCNA5KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547523-B1 | Ethanolates of 6-sulfonylsubstituted 3-hydroxychromanes and their use as inhalation means for illnesses | HOECHST AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| US-5310753-A | Ethanol adducts of 6-sulfonyl-substituted 3-hydroxy-chromans and their use as inhalants in diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| EP-0547523-A1 | Ethanolates of 6-sulfonylsubstituted 3-hydroxychromanes and their use as inhalation means for illnesses | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | disclosed |