Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 12/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 12/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200746 | 1.00 | KCNE1 (0.45) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9200759 | 1.00 | KCNE1 (0.45) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9200412 | 0.85 | KCNE1 (0.45) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9200392 | 0.85 | KCNE1 (0.45) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9200400 | 0.85 | KCNE1 (0.45) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9475562 | 0.84 | ALDH1A1 (0.43) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9205841 | 0.84 | ABCC9 (0.54) | KCNE1KCNQ1ABCC9KCNA5 | |
| SCHEMBL9200860 | 0.84 | ABCC9 (0.54) | KCNE1KCNQ1ABCC9KCNA5 | |
| SCHEMBL9475581 | 0.84 | ALDH1A1 (0.43) | KCNE1KCNQ1ABCC9MEN1CYP1A2 | |
| SCHEMBL9475568 | 0.84 | ALDH1A1 (0.43) | KCNE1KCNQ1ABCC9MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389861-B1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5104890-A | Potassium channel activtors; vasodilators | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0389861-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |