Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201038 | 0.86 | LMNA (0.57) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| SCHEMBL11839398 | 0.84 | CES2 (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27935114 | 0.83 | LMNA (0.58) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| SCHEMBL11680180 | 0.82 | SERPINE1 (0.55) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| SCHEMBL27588015 | 0.81 | ESR1 (0.46) | LMNATDP1SERPINE1KMT2ANPC1 | |
| SCHEMBL2612527 | 0.81 | SERPINE1 (0.50) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| SCHEMBL8476252 | 0.80 | ELANE (0.53) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5986868 | 0.80 | RAB9A (0.60) | LMNACYP3A4MAPTTDP1MEN1 | |
| SCHEMBL25522371 | 0.79 | LMNA (0.56) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| SCHEMBL539733 | 0.78 | LMNA (0.59) | LMNACYP3A4MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981558-A | ANTIMICROBIAL ACTIVITY AND ANTITUMOR ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0918058-A1 | DC 107 DERIVATIVES (1) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-05-26 | — | — | EP | disclosed |