Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201097 | 1.00 | FAAH (0.53) | FAAHCNR2EZH2NR4A1NR4A2 | |
| SCHEMBL9396390 | 0.85 | MMP2 (0.56) | FAAHCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL9196805 | 0.85 | MMP2 (0.56) | FAAHCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL9196809 | 0.85 | MMP2 (0.56) | FAAHCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL9202511 | 0.84 | CNR1 (0.56) | FAAHCNR2EZH2NR4A1NR4A2 | |
| SCHEMBL9202517 | 0.84 | CNR1 (0.56) | FAAHCNR2EZH2NR4A1NR4A2 | |
| Hydrochloric Acid SCHEMBL7619875 | 0.82 | MMP2 (0.61) | EZH2NPC1NR1H4TAOK1 | |
| Hydrochloric Acid SCHEMBL7619870 | 0.82 | MMP2 (0.61) | EZH2NPC1NR1H4TAOK1 | |
| SCHEMBL11337013 | 0.81 | HSD17B10 (0.44) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11337008 | 0.81 | HSD17B10 (0.44) | NPC1RAB9ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |