Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198184 | 0.91 | MAPT (0.33) | CNR1CNR2GRM2GRM3MAPT | |
| SCHEMBL9203185 | 0.84 | TDP1 (0.34) | CNR1CNR2MAPTHTTNPSR1 | |
| SCHEMBL9195772 | 0.84 | EPHX1 (0.38) | CNR1CNR2MAPTHTTNPSR1 | |
| SCHEMBL9201208 | 0.83 | — | — | |
| SCHEMBL9199475 | 0.83 | KMT2A (0.36) | MAPTHTTNPSR1 | |
| SCHEMBL9270055 | 0.82 | MC5R (0.40) | MAPTNPSR1KDM4E | |
| SCHEMBL9196808 | 0.82 | MAPT (0.33) | MAPTHTTNPSR1 | |
| SCHEMBL9196838 | 0.82 | TDP1 (0.37) | CNR2MAPTHTTNPSR1KDM4E | |
| SCHEMBL9202319 | 0.82 | SLC1A5 (0.37) | — | |
| SCHEMBL9194700 | 0.82 | KMT2A (0.38) | MAPTHTTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |