Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | KYNU | Q16719 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203185 | 0.91 | TDP1 (0.34) | KMT2AMEN1MAPTHTTNPSR1 | |
| SCHEMBL9201579 | 0.89 | TRPM8 (0.38) | KMT2AMEN1TRPM8CTBP2 | |
| SCHEMBL9196808 | 0.88 | MAPT (0.33) | KMT2AMEN1MAPTHTTNPSR1 | |
| SCHEMBL9198354 | 0.88 | KMT2A (0.32) | KMT2AMEN1SMN1; SMN2MAPTHTT | |
| SCHEMBL9201326 | 0.86 | ALDH1A1 (0.37) | KMT2AMEN1SMN1; SMN2MAPTHTT | |
| SCHEMBL9195755 | 0.86 | ALDH1A1 (0.37) | KMT2AMEN1SMN1; SMN2GRM8GRM4 | |
| SCHEMBL9196838 | 0.85 | TDP1 (0.37) | KMT2AMEN1MAPTHTTNPSR1 | |
| SCHEMBL9194668 | 0.84 | TDP1 (0.39) | KMT2AMEN1SMN1; SMN2MAPTHTT | |
| SCHEMBL9198184 | 0.84 | MAPT (0.33) | MAPTHTTNPSR1 | |
| SCHEMBL9201153 | 0.83 | CNR1 (0.34) | MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |