Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194700 | 0.94 | KMT2A (0.38) | EPHX1ALOX5ALDH1A1KMT2AMAPT | |
| SCHEMBL9194668 | 0.91 | TDP1 (0.39) | EPHX1ALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL9202319 | 0.91 | SLC1A5 (0.37) | KMT2ATDP1 | |
| SCHEMBL9201579 | 0.84 | TRPM8 (0.38) | KMT2ATDP1MEN1TAS2R14CHRM1 | |
| SCHEMBL9201153 | 0.84 | CNR1 (0.34) | MAPTKDM4ECNR1CNR2HTT | |
| SCHEMBL9201326 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KMT2AMAPTTDP1GAA | |
| SCHEMBL9195755 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL9198184 | 0.81 | MAPT (0.33) | MAPTCNR1CNR2HTTNPSR1 | |
| SCHEMBL9203185 | 0.81 | TDP1 (0.34) | KMT2AMAPTTDP1MEN1CNR1 | |
| SCHEMBL9196838 | 0.80 | TDP1 (0.37) | ALDH1A1KMT2AMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |