Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203185 | 0.97 | TDP1 (0.34) | MAPTHTTNPSR1TDP1MEN1 | |
| SCHEMBL9203349 | 0.88 | — | — | |
| SCHEMBL9199475 | 0.88 | KMT2A (0.36) | MAPTHTTNPSR1MEN1KMT2A | |
| SCHEMBL9196838 | 0.88 | TDP1 (0.37) | MAPTHTTNPSR1TDP1MEN1 | |
| SCHEMBL9194668 | 0.87 | TDP1 (0.39) | MAPTHTTNPSR1TDP1MEN1 | |
| SCHEMBL9198354 | 0.85 | KMT2A (0.32) | MAPTHTTNPSR1TDP1MEN1 | |
| SCHEMBL9195383 | 0.84 | NR3C2 (0.35) | TDP1MEN1KMT2A | |
| SCHEMBL9201326 | 0.83 | ALDH1A1 (0.37) | MAPTHTTNPSR1TDP1MEN1 | |
| SCHEMBL9195755 | 0.83 | ALDH1A1 (0.37) | MAPTHTTNPSR1MEN1KMT2A | |
| SCHEMBL9198184 | 0.83 | MAPT (0.33) | MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |