Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195052 | 0.86 | CYP3A4 (0.43) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL9198981 | 0.85 | CYP3A4 (0.40) | SMN1; SMN2HSP90AA1NPSR1CYP19A1KMT2A | |
| SCHEMBL9196212 | 0.85 | GAA (0.46) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL9201132 | 0.83 | HSP90AA1 (0.38) | MAPTHSP90AA1NPSR1CYP19A1KMT2A | |
| SCHEMBL9201064 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL28602340 | 0.74 | HSP90AA1 (0.56) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL11547531 | 0.74 | HSP90AA1 (0.56) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL28612952 | 0.74 | HSP90AA1 (0.56) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL28604608 | 0.74 | HSP90AA1 (0.53) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 | |
| SCHEMBL11541496 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2HSP90AA1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431968-B1 | Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents | SANKYO CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5134152-A | 1,2,4-Triazole compounds | SANKYO COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0431968-A1 | Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents | Sankyo Company Limited (JP) | 1991-06-12 | — | — | EP | disclosed |