Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878874 | 0.94 | TRPA1 (0.42) | TRPA1HTR7NFE2L2KMT2AHPGD | |
| SCHEMBL6320373 | 0.89 | ALDH1A1 (0.39) | KMT2AHPGDLMNAMAPTNPSR1 | |
| SCHEMBL653095 | 0.86 | NFE2L2 (0.43) | TRPA1NFE2L2KMT2ALMNAMEN1 | |
| SCHEMBL1612718 | 0.80 | CYP2A6 (0.46) | NFE2L2HPGDL3MBTL1MAPTNPSR1 | |
| SCHEMBL15050819 | 0.79 | NFE2L2 (0.47) | TRPA1HTR7NFE2L2PTGS1PTGS2 | |
| SCHEMBL15050816 | 0.79 | NFE2L2 (0.47) | TRPA1HTR7NFE2L2PTGS1PTGS2 | |
| SCHEMBL654529 | 0.79 | NFE2L2 (0.48) | TRPA1NFE2L2KMT2ALMNAMEN1 | |
| SCHEMBL1611354 | 0.78 | ALDH1A1 (0.46) | KMT2AHPGDL3MBTL1PTGS1PTGS2 | |
| SCHEMBL27916482 | 0.78 | LMNA (0.44) | KMT2AHPGDL3MBTL1LMNAMEN1 | |
| SCHEMBL6422361 | 0.78 | ALDH1A1 (0.47) | KMT2APTGS1PTGS2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |