Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204136 | 0.79 | CA2 (0.37) | CA12CA1CA2CA4CA6 | |
| SCHEMBL9201775 | 0.76 | KDM4E (0.43) | CA12CA1CA2CA4CA6 | |
| SCHEMBL8629678 | 0.71 | CA1 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL762724 | 0.71 | — | — | |
| SCHEMBL10745258 | 0.71 | KDM4E (0.37) | CA12CA1CA2CA4CA6 | |
| SCHEMBL19402522 | 0.69 | CDK8 (0.42) | MAPTHPGDHTT | |
| SCHEMBL27529948 | 0.68 | LMNA (0.40) | PTGS1PTGS2MAPTHTT | |
| SCHEMBL11985913 | 0.66 | — | — | |
| SCHEMBL20704250 | 0.66 | KDM4E (0.32) | MAPTHPGDHTT | |
| SCHEMBL10574711 | 0.64 | KDM4E (0.42) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350176-B1 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL IND LTD (JP) | 1995-08-30 | — | — | EP | claimed |
| US-5053517-A | PROCESS FOR PREPARING PYRAZOLECARBOXYLIC ACID COMPOUNDS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-01 | — | — | US | claimed |
| EP-0350176-A2 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-01-10 | — | — | EP | claimed |
| EP-0350176-B1 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL IND LTD (JP) | 1995-08-30 | — | — | EP | disclosed |
| US-5202442-A | Process for preparing pyrazolecarboxylic acid compounds | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5053517-A | PROCESS FOR PREPARING PYRAZOLECARBOXYLIC ACID COMPOUNDS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0350176-A2 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |