SCHEMBL9201775

SCHEMBL9201775

Cc1nn(C)c(S(N)(=O)=O)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CA12 O43570 4/20 0.35
CA2 P00918 4/20 0.35
CA9 Q16790 4/20 0.35
CA1 P00915 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NMT1 P30419 1/20 0.34
ABL1 P00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202089 0.82 KDM4E (0.41) KDM4EKMT2AMEN1CA12CA2
SCHEMBL13683113 0.82 KDM4E (0.41) KDM4EKMT2AMEN1CA12CA2
SCHEMBL10204136 0.79 CA2 (0.37) KDM4ECA12CA2CA9CA1
SCHEMBL9201434 0.76 CA12 (0.35) PTGS1PTGS2CA12CA2CA9
SCHEMBL1626536 0.72 L3MBTL1 (0.42) KDM4ECA12CA2CA9CA1
SCHEMBL10574711 0.72 KDM4E (0.42) KDM4EKMT2AMEN1CA12CA2
SCHEMBL9199353 0.71 SMN1; SMN2 (0.36) CA12CA2CA9CA1CA4
SCHEMBL9196910 0.71 PKM (0.59) KDM4EALDH1A1SMN1; SMN2ALPLLMNA
SCHEMBL10578072 0.68 L3MBTL1 (0.46) KDM4EKMT2AMEN1CA12CA2
SCHEMBL30845963 0.68 FPR2 (0.35) KDM4EKMT2AALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6009317-A None JP disclosed
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
JP-H069317-A PYRAZOLESULFONYLUREA DERIVATIVE, ITS PRODUCTION AND SELECTIVE HERBICIDE CONTAINING THE SAME DERIVATIVE NISSAN CHEM IND LTD 1994-01-18 JP disclosed
CN-1015107-B Process for producing pyrimidine or triazine derivative TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1991-12-18 CN disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
US-4872901-A PREFERENTIAL TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-10 US disclosed
CN-86107113-A Herbicidal compounds, process for their preparation and their use 1987-05-27 CN disclosed
EP-0220695-A1 Herbicidal compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-05-06 EP disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed