Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197634 | 0.87 | ENO1 (0.41) | ENO1L3MBTL1CCR2ALDH1A1KDM4E | |
| SCHEMBL5210529 | 0.71 | MMP1 (0.38) | L3MBTL1CCR2HTT | |
| SCHEMBL5210522 | 0.71 | CCR2 (0.35) | ENO1L3MBTL1CCR2ALDH1A1HTT | |
| SCHEMBL1105058 | 0.69 | — | — | |
| SCHEMBL1105059 | 0.69 | — | — | |
| SCHEMBL2785455 | 0.69 | — | — | |
| SCHEMBL11290940 | 0.67 | ENO1 (0.48) | ENO1 | |
| SCHEMBL20008739 | 0.66 | — | — | |
| SCHEMBL22288208 | 0.65 | KDM4E (0.31) | ALDH1A1KDM4E | |
| SCHEMBL24740592 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411664-B1 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5095013-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0411664-A2 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |