SCHEMBL11495679

SCHEMBL11495679

C=CCc1ccc(C(C)(C)C)c(O)c1CC=C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 7/20 0.42
GABRB2 P47870 7/20 0.42
CA2 P00918 1/20 0.41
GAA P10253 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
KMT2A Q03164 2/20 0.34
AKR1B1 P15121 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALDH2 P05091 1/20 0.34
HPGD P15428 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
POLB P06746 2/20 0.34
ALOX12 P18054 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9754486 0.84 GABRA1 (0.43) GABRA1GABRB2CA2GAAMEN1
SCHEMBL10413004 0.84 GABRA1 (0.43) GABRA1GABRB2CA2GAAAKR1B1
SCHEMBL9201480 0.82 GABRA1 (0.44) GABRA1GABRB2CA2GAAMEN1
SCHEMBL1005361 0.81 GABRA1 (0.55) GABRA1GABRB2GAAMEN1MAPT
SCHEMBL9540483 0.79 CA2 (0.45) GABRA1GABRB2CA2GAAMEN1
SCHEMBL1980875 0.79 GABRA1 (0.59) GABRA1GABRB2CA2GAAMEN1
SCHEMBL5849196 0.78 GABRA1 (0.44) GABRA1GABRB2GAAMEN1MAPT
SCHEMBL7943871 0.77 GABRA1 (0.52) GABRA1GABRB2GAAMEN1MAPT
SCHEMBL4543641 0.76 ALDH1A1 (0.52) GABRA1GABRB2GAAMEN1MAPT
SCHEMBL9028212 0.76 GABRA1 (0.33) GABRA1GABRB2CA2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4236032-A FROM 3-ALKYLPHENOLS OR 2,3-DIALKYLPHENOLS CONOCO, INC. (US) 1980-11-25 US claimed